Salk Institute for Biological Studies

  Job #: G993 Posted Date: April 1, 2020 Closes On: Open Until Filled Job Title: Lab Tech I - Plant Molecular and Cellular Biology Laboratory, Dr. Wolfgang Busch Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Plant Molecular and Cellular Biology Laboratory Position Description: Under close supervision, position will perform tasks and experiments in support of academic research projects. Position will be part of plant research group studying the genes involved in Arabidopsis root growth. Responsibilities may include: preparing media plates, overseeing plating of seeds by a robot and/or plating seeds, scanning media plates on flatbed scanner, simple data analysis, watering plants, and general lab maintenance. Education: Required: Undergraduate coursework in biological sciences or related field, or combination of high school diploma (or equivalent) with relevant...

  Job #: G980 Posted Date: April 29, 2020 Closes On: Open Until Filled Job Title: Animal Health Technician I Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Animal Resources The ARD is dedicated to providing the highest quality of veterinary medical care, husbandry, enrichment and professional technical support to enable the scientists and their research. Position Description: This position is responsible for routine processing of clean and soiled cages and accessories, maintenance and general janitorial duties in animal facilities, equipment maintenance, basic QA testing, processing deliveries from vendors and performing basic rodent husbandry tasks based on standard operating procedures and training to ensure compliance with the Guide for the Care and Use of Laboratory Animals, the Animal Welfare Act and Regulations as well as all applicable federal, state, local and...

  Job #: H065 Posted Date: May 1, 2020 Closes On: Open Until Filled Job Title: Greenhouse Research Technician - Plant Molecular and Cellular Biology Laboratory, Dr. Joanne Chory Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Plant Molecular and Cellular Biology Laboratory Laboratory is interested in identifying the mechanisms by which plants respond to changes in their light environment. Position Description: The CRoPS project aims to develop crop plants that sequester more carbon via extensive root systems containing recalcitrant carbon polymers to fight climate change. A major component of this research is to grow, test and analyze a variety of plant strains and species. The Greenhouse Research Technician will assist in the daily research operations of the greenhouse, and in all plant culture related areas of the CRoPS project. The Greenhouse Research Assistant will...

Job #: H069 Posted Date: April 28, 2020 Closes On: Open Until Filled Job Title: Bioinformatics Analyst I - Regulatory Biology Laboratory, Dr. Satchidananda Panda Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Regulatory Biology Laboratory Research in the lab is geared towards identifying molecular components and events critical for transmitting light information from the eye to the master oscillator in the brain. Position Description: The Regulatory Laboratory at the Salk Institute uses data science tools to analyze large scale data ranging from genomics to human lifestyle...

  Job #: H081 Posted Date: April 29, 2020 Closes On: Open Until Filled Job Title: Clinical Veterinarian- Animal Resources Department Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Animal Resources Department The ARD is dedicated to providing the highest quality of veterinary medical care, husbandry, enrichment and professional technical support to enable the scientists and their research. Position Description: Position is responsible for provision of quality clinical veterinary care for all animals maintained at The Salk Institute. Responsible for preventative medicine, quarantine, surveillance, diagnosis, treatment and control of disease, anesthesia and analgesia, surgery and post-surgical care, euthanasia and clinical services directly related to research protocols. Position serves as a critical liaison between research investigators and the Animal Resources Department...

  Job #: H064 Posted Date: April 22, 2020 Closes On: Open Until Filled Job Title: Research Assistant I - Plant Molecular & Cellular Biology Laboratory, Dr. Julie Law Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Plant Molecular and Cellular Biology Laboratory Position Description: The CRoPS project aims to develop crop plants that sequester more carbon via extensive root systems containing recalcitrant carbon polymers to fight climate change. A major component of this research is to conduct genetic and genomic analysis for understanding traits relevant for this. The Research Asst I will work closely with a Research Asst III, and other members of the CRoPS project and the Law laboratory in identifying plants with roots that store more carbon biopolymers while maintaining normal root function and morphology using various molecular biology and microscopy techniques. The RAI...

  Job #: G988 Posted Date: April 10, 2020 Closes On: Open Until Filled Job Title: Science Writer - Peptide Biology Laboratory, Dr. Alan Saghatelian Status: Regular Full Time Benefits Eligible: Yes Position Description: Writes and/or edits complex content for grant proposals, peer-reviewed publications, patents and communications. In collaboration with faculty and lab members, prepares grant applications and papers pertaining to new frontiers in cancer, virology, structural biology, synthetic biology, imaging, molecular biology and biotechnology. Ideal person is responsible for editing and coordinating the written content-technical and stylistic-together with associated figures for papers and grant proposals with the lab members and faculty. He or she must be able to meet proposal submission deadlines and funding goals, relate scientific and strategic goals to individual grant opportunities, and remain informed...

  Job #: G941 Posted Date: January 9, 2020 Closes On: Open Until Filled Job Title: Postdoctoral Fellow - Integrative Biology Laboratory, Dr. Graham McVicker Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Integrative Biology Laboratory The McVicker laboratory studies how human genetic variation affects gene regulation by combining experimental approaches with computational analyses. We are especially interested in identifying pathogenic regulatory variants that act in immune cells and cancer cells. Currently, we are developing new tools to discover somatic regulatory mutations in cancer genomes, and manipulating cell lines with high-throughput CRISPR technologies to discover new regulatory sequences. In much of our research, we develop sophisticated computational and statistical methods so that we can extract subtle signals from noisy experimental data. Position Description:...

  Job #: G811 Posted Date: April 10, 2020 Closes On: Open Until Filled Job Title: Senior Director & Attending Veterinarian - Animal Resources Department Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Animal Resources The Animal Resources Department is dedicated to providing the highest quality of veterinary medical care, husbandry, enrichment and professional technical support to enable the scientists and their research. Position Description: The Salk Institute for Biological Studies is ranked as one of the top 5 basic research institutes in the world. This world class facility now seeks a highly trained laboratory animal veterinarian and executive to lead our Animal Resources Department. Position is responsible for the ongoing development and daily operations of all Salk vivaria (approx. 47,000 square feet) including laboratory animal management, veterinary care and...

  Job #: G972 Posted Date: April 10, 2020 Closes On: Open Until Filled Job Title: Sr. Director, External Relations Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Development The Development department has primary responsibility to implement and execute strategies to meet Salk's specific fundraising needs through local, national and international philanthropic efforts. Position Description: Reporting directly to the Vice President, External Relations (VPER), the Senior Director, External Relations will have the responsibility for building a principal gifts program ($1M+ gifts) for individual and foundation donors primarily for the Optimal Aging Initiative at the Salk Institute for Biological Sciences, as well as other initiatives and fundraising programs as assigned. The Senior Director will create strategies, implement plans and set clear annual fundraising goals with the...

Job #: F259 Posted Date: December 28, 2019 Closes On: Open Until Filled Job Title: Postdoctoral Fellow - Clayton Foundation Laboratories for Peptide Biology, Dr. Marc Montminy Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Clayton Foundation Laboratories for Peptide Biology Our laboratory studies how extracellular signals trigger changes in metabolic energy balance via the activation of specific genetic programs. A number of growth factors and hormones activate cellular gene expression via the phosphorylation of key transcription factors and coactivators. As the first nuclear factor shown to be regulated by...

  Job #: G927 Posted Date: December 19, 2019 Closes On: Open Until Filled Job Title: Postdoctoral Fellow - Integrative Biology Laboratory, Dr. Edward Stites Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: The Integrative Biology Laboratory The Stites Laboratory studies the relationships between mutations, cancer (and other diseases), and the response to treatment. Projects typically involve a combination of experimental and computational biology, and most members of the lab are either traditional experimental biologists or purely computational scientists. Position Description: The Stites lab is looking for experimental postdoctoral researchers who work in cancer biology, cell biology, and or biochemistry. Multiple hypothesis-driven experimental projects for which a computational biology foundation is already present are available for motivated experimental postdocs to take...

  Job #: G826 Posted Date: April 10, 2020 Closes On: Open Until Filled Job Title: Senior Systems Engineer Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Information Technology The IT department operates and maintains the Institute's core network / compute / storage infrastructure and provides engineering and operational support services to labs and administrative departments. Position Description: Under general direction and reporting to the Information Technology Manager, provides systems engineering and operational management of technology infrastructure supporting data and compute-intensive research laboratories. Additionally, provides engineering and operational support for administrative systems and core technology services. Position requires research, design, planning, installation, configuration, operation and maintenance of complex infrastructure platforms...

  Job #: F289 Posted Date: October 1, 2018 Closes On: Open Until Filled Job Title: Research Associate - Regulatory Biology Laboratory, Dr. Katherine Jones Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Regulatory Biology Laboratory Lab research focuses on gene transcription, emphasizing the role of transcription elongation and RNAPII CTD kinases in cancer and human embryonic stem cell differentiation. Position Description: A postdoctoral position is available to study a newly-discovered pathway, which links transcription and RNAPII CTD kinases with mRNA 5-cap remodeling by mTORC1 for facilitated translation in the cytoplasm, is critical for ovarian, breast and prostate cancer metastases. The project will explore how the CDK12 kinase affects signaling under NRF2/oxidative stress conditions, as well as during human embryonic stem cell renewal and differentiation. A novel...

  Job #: G910 Posted Date: December 12, 2019 Closes On: Open Until Filled Job Title: Postdoctoral Fellow - Gene Expression Laboratory, Dr. Geoffrey Wahl Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Gene Expression Laboratory The research focuses on important problems related to cancer initiation, detection, progression, metastasis and treatment. These projects are based on our recent observations concerning cell state plasticity that arises during cancer progression. Specifically, we are using a single cell RNA sequencing, epigenetic profiling, and developing novel in vivo and in vitro strategies involving mouse models and organoid cultures to determine how cancer cells undergo developmental reprogramming to generate intra-tumoral heterogeneity and metastasis. We use computational methods based on mouse cancer models and human databases. Our work has focused significantly on breast...

  Job #: A028 Posted Date: April 22, 2016 Closes On: Open Until Filled Job Title: Research Associate - Molecular Neurobiology Laboratory, Dr. Sreekanth Chalasani Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Molecular Neurobiology Laboratory Work in the lab is centered on understanding how neural circuits in the brain transfrom environmental stimuli into appropriate behavioral outputs. Position Description: We are seeking post-doctoral fellows to study how the nervous system responds to changes in the environment and executes behaviors. We are also actively seeking engineers who are interested in technology development. We use a combination of genetics, behavior analysis, and imaging in the C.elegans and zebrafish models. Education: A strong background in cell biology, genetics, molecular biology, neuroscience or engineering is preferred. Application...

  Job #: F496 Posted Date: February 23, 2017 Closes On: Open Until Filled Job Title: Research Associate/Postdoctoral Scientist - Translational Research (Immunology/Oncology) Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Molecular and Cell Biology Laboratory Laboratory employs the help of a small DNA virus, called adenovirus, to both understand and treat cancer. DNA viruses and tumor cells sabotage such controls to drive their respective pathological propagation, albeit with one small difference: In tumor cells the key cellular players are targeted via mutations, while in infected cells viral proteins achieve the same end. Not surprisingly, many of the cellular targets are the same. Dr. O'Shea's lab is exploiting this overlap to help address three key questions: What are the critical cellular targets and pathways that drive deregulated growth? What is the human growth deregulation...

  Job #: E423 Posted Date: September 8, 2014 Closes On: Open Until Filled Job Title: Research Associate - Laboratory of Genetics, Dr. Fred Gage Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Laboratory of Genetics Lab research concentrates on the adult central nervous system and unexpected plasticity and adaptability to environmental stimulation that remains throughout the life of all mammals. Position Description: Post-doctoral fellow with significant electrophysiological training who will work on his/her own project and collaborate with other fellows in the lab.   Education: PhD degree in Neurophysiology is required.   Experience: Required:   Expertise in single cell patch-clamp physiology Hippocampal slice electrophysiology   Preferred:   Human embryonic stem cell...

Job #: F672 Posted Date: July 18, 2017 Closes On: Open Until Filled Job Title: Research Associate - Vision Center Laboratory, Dr. Thomas Albright Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Vision Center Laboratory Nearly every facet of human experience is colored by the sense of sight. The effortlessness and immediacy with which this sense conveys physical, social, and aesthetic qualities of one's environment belie the extraordinary complexity of the brain mechanisms involved. Our acute dependence upon these mechanisms is brought to the fore, however, by a variety of developmental, traumatic, and disease-related...

Job #: G078 Posted Date: May 29, 2018 Closes On: Open Until Filled Job Title: Research Associate - Molecular Neurobiology Laboratory, Associate Director, Nicola Allen Status: Regular Full Time Benefits Eligible: Yes Laboratory/Department: Molecular Neurobiology Laboratory The goal of the lab is to identify how non-neuronal brain cells, specifically astrocytes, regulate the formation, function and stability of neuronal synapses. This is achieved through a combination of in vitro and in vivo approaches, to investigate synapse formation in development, synaptic remodeling during plasticity, and synapse loss in aging and neurodegenerative disease....