52 jobs found in san diego

The Harnessing Plants Initiative (HPI) is developing crop and wetland plants that will store more carbon, longer, to reduce atmospheric CO2 and mitigate climate change. Within HPI, there are two tracks: CO2 Removal on a Planetary Scale (CRoPs) and Coastal Plant Restoration (CPR). The CRoPS track is developing crop plants that sequester more carbon via extensive root systems containing recalcitrant carbon polymers to fight climate change. A major component of this research is to conduct genetic and genomic analyses for understanding relevant traits and translation from model organisms to target crops. Many of the CRoPS projects depend on genomics data, including gene expression analysis and genome building/annotation. The Bioinformatics Analyst I will work on several genomics research projects, most notably with next-generation sequencing datasets, independently and/or under the supervision of senior analyst(s) and PI leadership. The analyst will contribute...

The Research Assistant I position is responsible for assisting with research in genetics and diseases of the nervous system. Candidate receives general instruction on routine work, detailed instructions on new assignments. Work is performed under direct supervision. Entry-level position. Working as part of a team, candidate will assist in the procurement, maintenance, and analysis of mouse models of Alzheimer's disease. This includes but not limited to animal husbandry, colony management, PCR, DNA and RNA extractions and perfusions, tissue collection, histology, immunohistochemistry, confocal imaging, and presentation of results in a group meeting. The candidate will learn techniques required to collect, slice, and dissect fresh brain tissue for experimental samples. Position requires detailed reporting of research and experiments and delivery of these reports in written and verbal forms. ESSENTIAL FUNCTIONS (70%) The Research Assistant I position...

The Research Assistant I is responsible for cell biology and microscopy research in support of the Principal Investigator's (PI) studies. Duties involve cell culture work with a range of cellular systems, viral infections, fluorescence microscopy, and sample preparation for electron microscopy (EM) studies. Duties may include performing advanced molecular biology and cell biology for mammalian cell culture, performing transfection, and viral transduction based on study design, fluorescent labeling, as well as cell imaging using the advanced resources in the Biophotonics Core Facility at the Salk Institute, in support of research projects aimed at addressing questions pertaining to in situ structural biology. The candidate will assist a postdoctoral associate with experimental design and direction and may also be involved in hiring new staff, supervising and assisting with training of junior lab staff (junior technicians, students, and volunteers), as necessary....

SUMMARY: This position will be assisting senior lab members in support of academic research projects. The work will be a combination of computational and experimental work. The computational aspects will include processing of videos, behavioral data and neural data, and applying a variety of statistical and machine learning (ML) tools to analyze it. The experimental aspects will include surgeries, behavior paradigms, extracellular neural signal recording (electrophysiology or calcium imaging), perfusion and histology with mice. DUTIES AND RESPONSIBILITIES: Mouse Handling and Behavioral Assays Performs Neurobiological Techniques such as Immunohistochemistry, Fluorescent Microscopy, and Calcium Imaging & Analysis. Data Processing which includes scoring behavioral data. Assists with general Lab Support including preparation of reagents, stocking and organizing incoming lab supplies, and cleaning glassware and equipment as needed. Performs other...

The Lee Group in the Peptide Biology Laboratory at the Salk Institute focuses on understanding the logic of brain disease using an integrative and whole brain network (e.g., graph theory), multi-scale and multiple-modal approach that include single neurons-barcoding for BRICseq, multiomic sn-RNAseq and sn-ATACseq, spatial transcriptomics and proteinomics, machine learning, circuit mapping, in vivo physiological recording, optogenetics, large-scale unbiased behavioral screen, stem cells and gene-editing in non-rodent species. The Bioinformatics Analyst position will work closely with the PI and other members of the lab to analyze multiomics and multi-modal data generated in the lab. The BA will be responsible for executing and maintaining current analysis pipelines, building new analysis pipelines, and integrating new genomics tools when appropriate. The BA will also work closely with members in several collaborators for integrated analysis and interpret...

  POSITION SUMMARY This position is responsible for routine processing of clean and soiled cages and accessories, maintenance and general janitorial duties in animal facilities,  equipment maintenance, basic QA testing, processing deliveries from vendors and performing basic rodent husbandry tasks based on standard operating procedures and training to ensure compliance with the Guide for the Care and Use of Laboratory Animals, the Animal Welfare Act and Regulations as well as all applicable federal, state, local and institutional laws, regulations, policies and guidelines. ESSENTIAL FUNCTIONS PERFORMS THESE FUNCTIONS AND RESPONSIBILITIES BASED ON SOP AND TRAINING: CLEAN AND SOILED CAGE WASH OPERATIONS AHT 1, LEVEL A: Cleans, sanitizes and/or sterilizes rodent cages and accessories. Operates large cage washers and sterilizing equipment including rack washer, tunnel washer, autoclave, disposal units, automatic watering systems and...

POSITION SUMMARY The Research Assistant I position is responsible for performing various tissue and cell preparation techniques to analyze immune cells, microbiology and molecular biology techniques ; mouse handling and colony maintenance in support of the Principal Investigator (PI) and lab research goals. Other duties include assisting with general laboratory maintenance, including equipment maintenance, and ordering of supplies, etc. ESSENTIAL FUNCTIONS (50%) Immunology and Molecular/Cell Biology Techniques   Tissue processing for flow cytometry Culture of several bacterial strains (aerobic and anaerobic) Purification and manipulation of nucleic acids (e.g. RT-PCR, plasmid & genomic DNA preparation) RNA preparation, sequencing and analysis Culture of primary cells and cell lines Cryopreservation Suspension, matrix supported, and organoid culture (40%) Mouse Colony Handling and Maintenance   Mouse husbandry...

 The Stem Core Research Specialist will perform moderately complex laboratory procedures related to the use of human stem cells and derivation of somatic cell populations for disease modeling applications. This position will primarily support human cell modeling needs associated with multiple research centers on campus, including centers focused on novel cell modeling approaches for aging and Alzheimer's disease. DUTIES AND RESPONSIBILITIES: Performs direct conversion and differentiation workflows to generate neural cell lineages as well as other cell types. Independently performs functional and characterization assays related to these cell types. Plays a primary role in the production and distribution of specified cell types and organoids to meet the needs of research groups and centers supported by the Stem Cell Core. Develops existing and new protocols pertaining to the use of human somatic and human pluripotent cell lines for research purposes....

The Lab Tech II position is responsible for, with limited instruction for routine work, performing various cell and molecular biology and data handling techniques; library prep,  mouse handling and colony maintenance, minor mouse surgeries, mouse breeding and weaning, genotyping, flow cytometry and cell sorting, ELISA, RNA expression analysis in support of the Principal Investigator (PI) and lab research goals. Range of duties include, but is not limited to, data analysis and data base management, maintenance of tissue, DNA, and other experimental samples, assisting with general laboratory maintenance, including equipment maintenance, and ordering of supplies, and training of new personnel. Duties also include establishing and performing research and analysis on projects that involve the study of human and murine B cells.  May provide task instruction, training, and guidance to lower level personnel.  Carries out and analyzes experimental results with...

POSITION SUMMARY Research Assistant II position will focus on cell and molecular biology of cultured cells and organoids. A successful candidate will work half of their time on independent projects and the other half on supporting postdoctoral researchers in the lab. The position will be responsible for establishing and utilizing cell-based assays for evaluating the function of candidate genes, pharmacological agents, or secreted molecules and performing molecular biological experiments to characterize the mode of action. Position will be trained in specific techniques and methods in order to execute experiments that are broadly designed by post doc or PI and must be able to carry out and analyze experimental results independently. The overall goal of the research is to understand the molecular and biochemical function of circadian clock components and interacting genes. ESSENTIAL FUNCTIONS (50%) Tissue Culture Independently maintains cultures...

POSITION SUMMARY Provides general administrative (executive level) support to the PI's and affiliated lab groups including general department administration management and assistance and coordination of new and ongoing department undertakings.  Provides complex professional-level work in the assigned functional areas of budget and financial analysis for labs. Creates and maintains all financial reports including revenue and expense reports.  Prepares revenue forecasts and annual budgets for review.  Works closely with Institute departments such as Research Accounting, Grants, Payroll, Human Resources, Grant Administration, Computing, Communications, etc. Coordinates with other executive level administrative and project managers for scheduling and other organizational purposes. Uses initiative, resourcefulness and good judgment to handle a wide variety of administrative and support duties such as project management, addressing inquiries, maintaining filing...

  SUMMARY: The Research Assistant II position will work both independently and collaboratively as part of a focused group of researchers that studies how maternal factors influence their offspring's immune system in early life and adulthood. DUTIES AND RESPONSIBILITIES: Assists with mouse models and mouse colony maintenance including genotyping, animal husbandry, and monitoring. Performs cellular and molecular biology techniques which can include cell culture, tissue preparations, flow cytometry, bacterial culture etc. Analyzes and interprets scientific data using a variety of techniques. Performs related laboratory support and maintenance such as assisting with preparing standard solutions, stocking and weekly inventory, and organizing incoming lab supplies. Performs other related duties as assigned by management. SUPERVISORY RESPONSIBILITIES: This job has no supervisory responsibilities. QUALIFICATIONS: Minimum 2...

  SUMMARY: The Veterinary Technician I supports the Animal Resources department by providing laboratory animal care and training. Provides technical study support and routine diagnostic testing. Provides technical expertise to meet department/institutional goals and hands on training to uses of ARD databases and systems. DUTIES AND RESPONSIBILITIES: Monitors & observes animal health care daily; administers medications/treatments as needed and/or as directed. Performs regular health checks of animals, as well as routine health surveillance in sentinel animals which can include in-house diagnostic tests and collection/preparation of samples for outside diagnostic testing. Maintains clinical records on animals under veterinary care. Assists with semi-annual physicals/tb test on NHP; as well as assists the Veterinarians with non-research surgeries and follow-up veterinary care. Performs humane euthanasia as needed and/or as directed....

SUMMARY: Under direct supervision, the Research Assistant I position is part of a multidisciplinary team studying epigenetics, chromatin structure, and gene expression.  Responsibilities include, but are not limited to, performing techniques related to cell and molecular biology and biochemistry. Tasks include the maintenance of tissue, DNA, and other experimental samples, as well as taking part in data analysis and experimental planning.  Other duties include assisting with general laboratory maintenance, equipment maintenance, and ordering of supplies. LAB SUMMARY: The Dixon Lab seeks to understand how our genomes are organized in 3D space, and how this contributes to gene regulation and human disease. The lab using a combination of cutting edge genomics methods, including next generation sequencing and single-cell sequencing, as well as computational tools, to understand global patterns of genome organization. We have had a particular focus on how...

  The Research Assistant II position will work both independently and collaboratively as part of a focused group of researchers that studies how epigenetic regulation and the tumor microenvironment contribute to pancreatic cancer progression and therapeutic responses. DUTIES AND RESPONSIBILITIES: Assists with In Vivo Tumor Biology and colony maintenance including genotyping, animal husbandry, and monitoring. Performs cellular and molecular biology techniques which can include Cell Culture, flow cytometry, CRISPR/Cas9 screening, etc. Analyzes and interprets scientific data using a variety of techniques including Ultrasound analysis, Western blot, and DNA and RNA expression. Performs related laboratory support and maintenance such as assisting with preparing standard solutions, stocking and weekly inventory, and organizing incoming lab supplies. Performs other related duties as assigned by management. SUPERVISORY RESPONSIBILITIES: This...

The Research Assistant I position will work both independently and collaboratively as part of a focused group of researchers that studies how epigenetic regulation and the tumor microenvironment contribute to pancreatic cancer progression and therapeutic responses. DUTIES AND RESPONSIBILITIES: Assists with In Vivo Tumor Biology and colony maintenance including genotyping, animal husbandry, and monitoring. Performs cellular and molecular biology techniques which can include Cell Culture, flow cytometry, CRISPR/Cas9 screening, etc. Analyzes and interprets scientific data using a variety of techniques including Ultrasound analysis, Western blot, and DNA and RNA expression. Performs related laboratory support and maintenance such as assisting with preparing standard solutions, stocking and weekly inventory, and organizing incoming lab supplies. Performs other related duties as assigned by management. SUPERVISORY RESPONSIBILITIES: This job has...

Job location is at 441 Saxony Road, Encinitas, Ca 92024 The CRoPS project aims to develop crops that sequester more carbon via extensive root systems containing recalcitrant carbon polymers to fight climate change. A major component of this research are field experiments to understand the edaphic or soil factors affecting root traits and root trait-derived soil organic carbon (SOC). The Field Research Assistant will assist in collecting data in field research operations throughout the United States. This will involve aspects of agronomy, soil science and crop physiology to understand how root traits affect SOC accumulation and stability. The Field Research Assistant will play a key role in organizing, tracking, and processing soil and plant samples from field experiments. Field data collection includes soil coring and root washing, on location, throughout the United States. Sample preparation activities are conducted at Salk facilities and include:...

Job location   is at  10240 Science Center Dr,  San Diego, CA 92121 The Senior Director for Stewardship is a leadership position at the Salk Institute on the External Relations (ER) team.  The Senior Director is responsible for all Stewardship activities, including: prioritization of data integrity and CRM management and oversight; data analytics and donor portfolio management; metrics management; data-driven donor research and analytics; strategic programming management and oversight; alumni programming and related strategy; donor and endowment data analysis and related reporting; generation, analysis and management of various reports using enterprise systems; management of the Stewardship team; and close coordination with fellow Senior Directors and Directors on the ER team.  The Senior Director performs a critical important role in the daily management of the care of donor relationships at the Salk Institute. ESSENTIAL FUNCTIONS The Senior...

The Salk Biocomputation Initiative focuses on the data intensive needs present in biological science research today.  Large datasets are routinely generated by genome sequencing, gene expression profiling, advanced microscopy & video imaging to name a few experimental techniques. The Institute must manage the storage, transfer and processing of this data, both on-premise but also by using the capabilities available in the cloud. This position will design, implement and support the Institute's framework for cloud computing, working collaboratively with scientists to migrate their data pipelines to the cloud.  As part of the initiative, the position will provide training needed for longterm sustainable cloud-based compute and data storage in support of reasarch at Salk.  The position will assist hundreds of investigators and core facilities to accelerate and achieve research goals.  Reporting to the Executive Director Research Operations and as a domain...

The Lee Group in the Peptide Biology Laboratory at the Salk Institute focuses on understanding the logic of brain disease using an integrative and whole brain network (e.g., graph theory), multi-scale and multiple-modal approach that include single neurons-barcoding for BRICseq, multiomic sn-RNAseq and sn-ATACseq, spatial transcriptomics and proteinomics, machine learning, circuit mapping, in vivo physiological recording, optogenetics, large-scale unbiased behavioral screen, stem cells and gene-editing in non-rodent species. The Bioinformatics Analyst position will work closely with the PI and other members of the lab to analyze multiomics and multi-modal data generated in the lab. The BA will be responsible for executing and maintaining current analysis pipelines, building new analysis pipelines, and integrating new genomics tools when appropriate. The BA will also work closely with members in several collaborators for integrated analysis and interpret...