75 jobs found

Application Instructions: Employment History Include your last ten (10) years of employment history, or length of your employment history if less, including all positions (even those that are not relevant to this position) and periods of unemployment. Incomplete information could disqualify you from further consideration. Under general supervision, supports Procurement Service's Logistics Operations by performing a variety of shipping, receiving, distribution, mail and various logistic services to the Institute. Exercises some judgment in accordance with established policies, guidelines, procedures, techniques, quality improvement objectives, and safety, environmental, and/or infection control standards.  Involves tasks that require training in shipping, receiving and mail service processes.  Follows appropriate protocols for cost effectiveness, on-time and accurate delivery and appropriate handling of confidential, perishable, priority or otherwise sensitive mail or...

  Application Instructions: Employment History  Include your last ten (10) years of employment history, or length of your employment history if less, including all positions (even those that are not relevant to this position) and periods of unemployment. Incomplete information could disqualify you from further consideration. Responsible for the preparation, submission, and management of a portfolio of grant, contract, and fellowship applications and awards and other agreements from external funding sources, primarily focused on private foundations and philanthropy. Assists faculty and External Relations staff with assessing grant application objectives and planning. Provides guidance and assistance to faculty and staff with proposal preparation, submission, and reporting. Provides support as needed to ensure that the faculty and research units maximize opportunities to secure external grant, contract, and fellowship funding. Prepares, submits and...

Assistant Professor & Program Director - CSOE - San Diego Alliant International University is a professional practice University committed to excellence in four areas: Education for Professional Practice, Scholarship, Multicultural and International Competence and Community Engagement. The University provides students with the highest quality of education through excellence and innovation in academic scholarship, applied training and research, and community service, particularly to underserved populations. Through its Mission, the University's goal is to equip students with the competencies they need to provide public benefit and make an impact in their communities by addressing major contemporary social issues. Core competencies of the University's training programs include cultural diversity, which is infused in courses and field placements and is manifest in the diversity of its students, faculty. Our Mission: Alliant International University prepares students for...

Admissions Counselor (On Campus Programs) - San Diego Alliant International University is a professional practice University committed to excellence in four areas: Education for Professional Practice, Scholarship, Multicultural and International Competence and Community Engagement. The University provides students with the highest quality of education through excellence and innovation in academic scholarship, applied training and research, and community service, particularly to underserved populations. Through its Mission, the University's goal is to equip students with the competencies they need to provide public benefit and make an impact in their communities by addressing major contemporary social issues. Core competencies of the University's training programs include cultural diversity, which is infused in courses and field placements and is manifest in the diversity of its students, faculty. Our Mission: Alliant International University prepares students for...

Application Instructions: Employment History Include your last ten (10) years of employment history, or length of your employment history if less, including all positions (even those that are not relevant to this position) and periods of unemployment. Incomplete information could disqualify you from further consideration. POSITION SUMMARY The Image Analysis Specialist will have a principal responsibility to develop machine learning-based software for image restoration and analysis. The position will collaborate with other light and electron microscopy researchers in the Biophotonics Core and the Institute to provide specific expertise for developing custom computer algorithms for complex and novel analyses of raw imaging data, computer data management and developing algorithms for microscopy operations. The position will apply existing image processing software to 2D and 3D images and videos and will also integrate data across different platforms (e.g....

The Panda and Engle Labs are recruiting for a joint post-doctoral position to study connective tissue regeneration. In this fully funded collaboration, we are seeking to identify conditions, cell types, and factors that promote muscle or tendon repair and regeneration using three-dimensional organoid models. Ultimately, we will test the ability of these factors to optimize performance and accelerate repair in pre-clinical models.  Position Description A post-doctoral position is immediately available for team-oriented individuals with tissue culture experience. Ideal candidates should be intellectually curious, well-organized and well-versed in constructive problem solving. Experience with organoids, connective tissue biology and mouse modeling is preferred. Highlights Large, multidisciplinary team project with multiple opportunities for integration, collaboration, and networking State-of-the-art organoid pharmacotyping experience Potential for translation to...

Description The Michael Group in the Plant Molecular and Cellular Biology Laboratory at the Salk focuses on sequencing, assembling and analyzing plant genomes. A broad objective is to build genome resources for plants with unique morphological or lifestyle characteristics (carnivorous, parasitic), minimal plants (duckweed), and crop wild relatives (CWR), to better understand plant genome organization and trait architecture. Currently we are working on several different strategies to generate chromosome-level haplotype-resolved polyploid genomes. In addition, we are developing new techniques to annotate (coding and non-coding) non-model plant genomes using single-cell sequencing, direct DNA modification detection, and computational approaches. We are developing reference-free pan-genome methods for integration into genome wide selection studies (GWAS) and genomic selection paradigms to link population level phenotypes to gene networks underlying environmental response and...

The laboratory of Dr. Daniel Hollern at the Salk Institute of Biological Studies Department of Immunobiology and Microbial Pathogenesis in La Jolla, California seeks to recruit a Postdoctoral Fellow to engage in immuno-oncology research. The main focus of the lab is to understand the immunological and molecular landscape of tumors with the goal of leveraging the immune component to promote anti-tumor immunity. In more detail, the lab is particularly interested in developing these approaches through the study of tumor infiltrating B cells and T cells. These studies will be pursued in syngeneic, orthotopic and genetically engineered mouse models as well as patient specimens.  The lab utilizes a multidisciplinary approach blending biologically appropriate models, molecular biology, and genomic analytical techniques including single cell and spatial transcriptomics and proteomics to interrogate pertinent questions in a number of in vitro and in vivo translational studies of breast...

The research focuses on important problems related to cancer initiation, detection, progression, metastasis and treatment. These projects are based on our recent observations concerning cell state plasticity that arises during cancer progression. Specifically, we are using a single cell RNA sequencing, epigenetic profiling, and developing novel in vivo and in vitro strategies involving mouse models and organoid cultures to determine how cancer cells undergo developmental reprogramming to generate intra-tumoral heterogeneity and metastasis. We use computational methods based on mouse cancer models and human databases. Our work has focused significantly on breast cancer, but new studies have taken us into exciting directions involving cell state reprogramming involving acinar-ductal metaplasia in the genesis of pancreas cancer. Our long-term goals are to devise novel strategies to intercept cells undergoing reprogramming to reduce the probability that drug resistant or metastatic...

The McVicker laboratory studies how human genetic variation affects gene regulation by combining experimental approaches with computational analyses. We are especially interested in identifying pathogenic regulatory variants that act in immune cells and cancer cells. Currently, we are developing new tools to discover somatic regulatory mutations in cancer genomes, and manipulating cell lines with high-throughput CRISPR technologies to discover new regulatory sequences. In much of our research, we develop sophisticated computational and statistical methods so that we can extract subtle signals from noisy experimental data. Position Description:   Quantitative trait mapping of single cell gene expression and chromatin traits The McVicker Laboratory at the Salk Institute for Biological Studies is seeking a postdoctoral fellow to tackle cutting-edge research problems in genetics, gene regulation and chromatin biology. The successful candidate will develop new statistical...

Nearly every facet of human experience is colored by the sense of sight. The effortlessness and immediacy with which this sense conveys physical, social, and aesthetic qualities of one's environment belie the extraordinary complexity of the brain mechanisms involved. Our acute dependence upon these mechanisms is brought to the fore, however, by a variety of developmental, traumatic, and disease-related disorders of visual perception and visually-guided behavior. While rarely life- threatening, such disorders can be profoundly debilitating, impairing activities that we have come to take for granted, such as reading, driving, or recognizing family and friends. We seek a thorough understanding of brain mechanisms of visual information processing, with the promise of effective treatment and remediation of disorders of vision, as well as insights into the nature of our conscious experience of the world. The specific aims of our research have been to identify how sensory signals in...

We have multiple post-doctoral positions available for computational researchers in Talmo Pereira's lab. Our work leverages computer vision and deep learning to solve biological problems across diverse application areas, including neuroscience, plant biology and cell biology. We are looking for candidates with a strong background in computational work and looking to work closely with experimentalists to develop and apply machine learning models to tackle biological problems. Potential project areas and associated approaches include: Movement phenotyping: pose estimation, multi-animal tracking, behavior segmentation/action recognition âPlant phenotyping: shape estimation, image segmentation, multi-view reconstruction Artificial neural network-based modeling: agent-based models, imitation learning, interpretable AI, generative sequence models, probabilistic programming Specific projects will involve collaboration with experimental labs working on motor control, social...

Application Instructions: Employment History Include your last ten (10) years of employment history, or length of your employment history if less, including all position (even those that are not relevant to this position) and periods of unemployment. Incomplete information could disqualify you from further consideration. Description:   The Kosuri Lab at the Salk Institute for Biological Studies seeks to recruit multiple Postdoctoral Fellows to engage in integrative biology research. The lab has two tracks: 1) single-molecule studies of protein-DNA interactions, using methods based on DNA origami and super resolution microscopy; and 2) Cardiac biology studies in mouse models and humans, using genetic and imaging approaches including new methods for single-cell spatial transcriptomics. The postdoctoral positions are for scientists looking to invent and deploy new technology to uncover foundational principles in biology. Ideal candidates are excited to join a...

Post-doctoral position available for individual interested in signal transduction, transcriptional regulation, and metabolism. Experience in RNA sequencing, chromatin immunoprecipitation, and in bioinformatics helpful. Candidate should enjoy working independently in a collaborative setting. Interest in metabolic physiology desirable; we have state of the art facilities to study the role of the CREB pathway in different metabolic states. Our lab also employs genetics to gain insight into the role of the CREB pathway in glucose and lipid metabolism as well as in the development of insulin resistance and type II diabetes. We use biochemical approaches to characterize regulatory components of the CREB pathway and to identify cellular CREB target genes that contribute to the underlying physiology. Mice with knockouts of CREB and CRTC family members in different tissues are employed to identify biological contexts in which this pathway is activated. Interested applicants with PhD or...

The goal in the lab is to understand the molecular and circuit mechanisms of reward-based action learning, focusing on the cortico-basal ganglia circuitry and dopamine function. Position Description:   We are currently seeking a highly motivated and independent postdoctoral fellow interested in studying the basal ganglia circuits and behavior. Research in the laboratory focuses on the molecular and circuit mechanisms of action learning and selection, using a combination of behavioral, optogenetics, slice/in vivo electrophysiology and imaging techniques. The successful candidate will employ electrophysiology and/or deep-brain imaging, together with viral tracing and optogenetics to dissect the function of specific cell types of basal ganglia circuitry in freely behaving mice. Education:   The candidate should hold a doctoral degree with a strong background in systems or cellular neuroscience. Experience:   Experience on slice or in vivo electrophysiological...

Position description Our research employs cross-disciplinary approaches (genetics, transcriptomics, circuit tracing, functional imaging, quantitative behavioral analyses) to elucidate the roles played by genes and neurons in social behavior. An ideal postdoctoral fellow candidate would have a demonstrated expertise in the following fields: Biochemistry and bioinformatics. We seek a candidate who has both bench and quantitative data analysis experience in transcriptomics. Using our 10X Genomics single cell transcriptome platform, we intend to characterize genes responsible for flexible behavioral modulations during social interactions in both flies and unconventional animal models, such as honey bees and paper wasps. Neurophysiology. We seek a candidate who is familiar with techniques for monitoring activities of neurons in vivo , such as electrophysiology and functional imaging. We are in the process of expanding our functional imaging capacity to be able to monitor...

The Busch Group aims to understand which genes, genetic networks, and molecular processes determine root growth and its responses to the environment. This research is directly leveraged in the pioneering CRoPS project that aims to develop crop plants that sequester more carbon via extensive root systems containing recalcitrant carbon polymers to fight climate change. For this we are working to enhance the carbon sequestration capacity in several important crop species. We are currently seeking a highly motivated and independent postdoctoral fellow interested in studying the mechanisms controlling root traits in Canola. The ideal candidate will be a plant biologist who has experience working with Canola and has expertise in root phenotyping, quantitative genetics and plant molecular biology. Ideal candidates should be intellectually curious, highly productive, driven to uncover new and impactful biology and to apply this knowledge to the larger problem of climate change, and...

The Stites Laboratory applies quantitative and systems approaches (both experimental and computational) to the study of cancer.  We primarily focus upon the RAS pathway due to its importance in cancer, the abundance of data on the pathway and its molecular components, and the ready availability of excellent reagents and methods.  We repurpose these data and methods to study RAS from a systems perspective.   The laboratory is comprised of both experimental biologists and computational biologists. Position Description:   The postdoctoral fellow will be the primary lead for a new research program in the laboratory.  The research project(s) in this program will extend the lab's established expertise in RAS biology, cancer biology, personalized medicine, and computational systems biology into the field of synthetic biology.  Envisioned projects will utilize a synthetic biology approach to investigate cancer development and new cancer treatment strategies.  The postdoctoral...

We have multiple post-doctoral positions available in the Towers lab. Our work combines basic cell biology techniques and physiologically relevant cancer models to ask how cancer cells adapt when essential cellular recycling processes are blocked. We are looking for self-motivated and inquisitive scientist to join the team. Applicants should have a solid background in cancer biology and/or cell biology techniques with an eagerness to learn more. Additional skills in mouse models of cancer, optogenetics, cell metabolism, autophagy, and/or mitochondrial biology would be preferred.  To learn more about the lab here: https://towers.salk.edu/ Responsibilities: Perform investigational studies to understand how cancer models to ask how cancer cells adapt when essential cellular recycling processes are blocked. Perform cell biology experiments and/or perform in-vivo experiments in animal models such as mice or zebra fish. Execute experiments independently and contribute to...

Laboratory research focuses on how genes and molecules orchestrate the development of an embryo. The knowledge obtained may help to discover new molecules and specific gene/cell treatments to prevent and cure diseases affecting mankind both in the adult and embryonic stages, as well as inducing endogenous in vivo regenerative responses that may allow for tissue and organ regeneration and slowing down the aging process. Position Description:   Funded post-doctoral positions are immediately available for individuals with a good grounding in molecular and/or developmental biology, methods such as CRISPR mediated genome editing, RNA sequencing and epigenetics. Knowledge of bioinformatics is also very desirable. Ideal candidates should be intellectually curious, productive, and enjoy working in a committed team effort to make these important projects succeed. The projects are well under way due to the efforts of a dedicated group of post-docs, technicians and undergrads....