Research Assistant I - Molecular and Cell Biology Laboratory, Dr. Clodagh O'Shea

  • Salk Institute for Biological Studies
  • La Jolla, San Diego, CA, USA
  • Jul 29, 2020
Full time   Biology/Biotechnology/Life Sciences

Job Description

    • Posted: July 20, 2020
  • Full-Time
  • Salk Main Campus

    La Jolla, CA, USA
    Salk Main Campus

    La Jolla, CA, USA
    +0 more less

Job Details


Application Instructions:

Employment History Include your last ten (10) years of employment history, or length of your employment history if less, including all position (even those that are not relevant to this position) and periods of unemployment. Incomplete information could disqualify you from further consideration.


The Research Assistant I position is responsible for assisting scientists within the Reinventing Biology and Medicine’s team in the execution of in vivo models to characterize novel therapies for cancer, diabetes, and auto-immune diseases. The focus of this position will be management of research breeding colonies and to help perform research animal models. The ideal candidate will have worked with animals previously, managed research mouse colonies, and is excited to learn how to conduct animal experiments. The candidate will be responsible for learning and assisting with all techniques associated with the models such as dosing through multiple routes, blood collection, tissue harvesting, IVIS animal imaging, inoculation of cells, etc.


(40%) Mouse Colony Management

  •  Management of research breeding colonies
  • Perform genotyping
  • Mouse husbandry

(50%) In vivo Experimental Techniques

  • Perform inoculation of human tumor cell lines into immune deficient mice
  • Assist other scientists with the monitoring of tumor growth by direct tumor measurements and via in vivo imaging (IVIS)
  • Perform dosing thru several routes, blood collection, tissue harvesting, and as well as other standard methods of animal experimentation techniques

(10%) Lab Support

  • Assist with data capture
  • Maintain a logically organized lab notebook
  • Attend group meetings



  •  No professional-level experience required if experience gained through completion of relevant undergraduate coursework.
  • Demonstrated experience with managing research animal colonies
  • Demonstrated experience with mouse handling, including routine husbandry


  • Experience with blood and tissue collection/sampling and routine injections (i.v., i.p., s.c.)
  • Demonstrated experience with tissue culture and aseptic technique
  • Experience with whole animal imaging (IVIS) preferred but not required



  •  Bachelor’s degree in biological sciences or equivalent work experience in lieu of degree



  •  Knowledge and experience of standard animal handling techniques
  • Skill in the operation and maintenance of various lab equipment
  • Ability to manage and track large numbers of samples meticulously without mix-up or cross contamination
  • Knowledge of standard laboratory management and safety procedures
  • Skill in the operation and maintenance of various lab equipment.
  • Demonstrated knowledge and experience with PC operating system, standard business office equipment and commonly used software and tools, such as Microsoft Office, electronic mail, and the internet.
  • Highly organized, effective at multitasking, adept at juggling changing priorities
  • Strong interpersonal skills, including tact, diplomacy, and flexibility. Ability to establish and maintain effective working relationships; interact with all levels of management


  •  Must be willing to work in an animal-related research environment.
  • Must be willing to work an adjusted schedule to support research needs.
  • Satisfactory completion of the Institute’s background investigation


This position requires constant adjusting focus, grasping, hearing, keying, analyzing, calculating, communicating, reading, reasoning, writing, working inside and in confined areas.


Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities

The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information. 41 CFR 60-1.35(c)

Application Details

When inquiring or applying for positions at the Salk Institute for Biological Studies, please also reference

Applicants with dual-career considerations can find university jobs such as professor jobs, dean jobs, chair / department head jobs, and other faculty jobs and employment opportunities at the Salk Institute for Biological Studies and at other institutions of higher education in the region on