Job #: H150
Posted Date: July 8, 2020
Closes On: Open Until Filled
Job Title: Research Assistant I - Molecular and Cell Biology Laboratory, Dr. Clodagh O'Shea
Status: Regular Full Time
Benefits Eligible: Yes
Laboratory/Department: Molecular and Cell Biology Laboratory
Laboratory employs the help of a small DNA virus, called adenovirus, to both understand and treat cancer. DNA viruses and tumor cells sabotage such controls to drive their respective pathological propagation, albeit with one small difference: In tumor cells the key cellular players are targeted via mutations, while in infected cells viral proteins achieve the same end. Not surprisingly, many of the cellular targets are the same. Dr. O'Shea's lab is exploiting this overlap to help address three key questions: What are the critical cellular targets and pathways that drive deregulated growth? What is the human growth deregulation program and how do we uncouple it for tumor therapy? Can we manipulate viruses as novel therapeutic agents that trigger the rapid lytic death of tumor cells but leave normal cells unharmed?
The Research Assistant I position is responsible for assisting scientists within the Reinventing Biology and Medicine’s team in the execution of in vivo models to characterize novel therapies for cancer, diabetes, and auto-immune diseases. The focus of this position will be management of research breeding colonies and to help perform research animal models. The ideal candidate will have worked with animals previously, managed research mouse colonies, and is excited to learn how to conduct animal experiments. The candidate will be responsible for learning and assisting with all techniques associated with the models such as dosing through multiple routes, blood collection, tissue harvesting, IVIS animal imaging, inoculation of cells, etc.
This position requires constant adjusting focus, grasping, hearing, keying, analyzing, calculating, communicating, reading, reasoning, writing, working inside and in confined areas.
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