Research Associate - Regulatory Biology Laboratory, Dr. Katherine Jones

  • Salk Institute for Biological Studies
  • La Jolla, San Diego, CA, USA
  • Apr 13, 2020
Full time   Biology/Biotechnology/Life Sciences Grants, Sponsored Programs, Research

Job Description


Job #: F289

Posted Date: October 1, 2018

Closes On: Open Until Filled

Job Title: Research Associate - Regulatory Biology Laboratory, Dr. Katherine Jones

Status: Regular Full Time

Benefits Eligible: Yes

Laboratory/Department: Regulatory Biology Laboratory

Lab research focuses on gene transcription, emphasizing the role of transcription elongation and RNAPII CTD kinases in cancer and human embryonic stem cell differentiation.

Position Description:

A postdoctoral position is available to study a newly-discovered pathway, which links transcription and RNAPII CTD kinases with mRNA 5-cap remodeling by mTORC1 for facilitated translation in the cytoplasm, is critical for ovarian, breast and prostate cancer metastases. The project will explore how the CDK12 kinase affects signaling under NRF2/oxidative stress conditions, as well as during human embryonic stem cell renewal and differentiation. A novel regulator of CDK12, which is essential for mitochondrial oxidative phosphorylation will also be characterized and studied for insights to inhibit this step in cancer. Prior experience with ChIP-seq,RNA-seq, imaging, and molecular and biochemical/proteomics techniques would be relevant.


PhD degree in Biological Sciences.


Recent PhD with experience with mammalian cell culture, protein biochemistry, chromatin and/or gene expression analysis including chromatin immunoprecipitation.

Application Instructions:

Application Instructions: Please email Curriculum Vitae, a statement of research interests, and three letters of reference to:


Application Details

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Application Deadline

Open Until Filled