Job #: F670
Posted Date: July 18, 2017
Closes On: Open Until Filled
Job Title: Research Associate - Nomis Center Immunobiology and Microbial Pathogenesis, Dr. Bjorn Lillemeier
Status: Regular Full Time
Benefits Eligible: Yes
Laboratory/Department: Nomis Foundation Laboratories for Immunobiology and Microbial Pathogenesis
The Lillemeier laboratory is part of the Nomis Center for Immunobiology and the WAITT Advance Biophotonics Center. Research in the laboratory focuses on how T cell activities and functions are initiated and controlled during adaptive immune responses. Using cutting edge imaging, structural and biological approaches the lab studies the organization of proteins in the space and time to uncover how T cell signaling pathways are assembled and dissociated. Our goal is to modulate molecular mechanisms of T cell signaling to alter immune responses and find alternatives to current immunotherapies.
A postdoctoral position is available to study the effects of mutations in signaling the molecules (specifically of Zap70 and Shp2) on T cell immune responses in vitro and in vivo. The goal of these studies is to determine if plasma membrane proximal signaling mechanisms can be targeted in the future immunotherapies. The study will utilize animals models for cancel and autoimmunity, as well as T cell lines and ex vivo primary T cells from wild type and TCR transgenic mice. The position requires a strong background in cell biology or cellular immunology. Experience with animal models and in molecular biology will be beneficial. A successful candidate will be trained in specific technologies and methods required for the project.
For more information on the Lillemeier lab, please visit our webpage Lillemeier Laboratory
Background in cellular immunology/biology and animal models (e.g. for autoimmunity and/or cancer) is preferred. Rudimentary skills in molecular biology are beneficial to the position.
Email Dr. Bjorn Lillemeier a brief cover letter describing your background and research interests, your CV, and contact information for 2-3 references.
Bjorn Lillemeier, Ph.D.
Nomis Center for Immunobiology and Microbial Pathogenesis
Waitt Advanced Biophotonics Center
Salk Institute for Biological Studies
10010 N Torrey Pines Rd
La Jolla, CA 92037
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