Research Assistant III – Electron Microscopy Specialty, Laboratory of Genetics, Dr. Lyumkis

  • Salk Institute for Biological Studies
  • La Jolla, San Diego, CA, USA
  • Jan 08, 2020
Full time   Biology/Biotechnology/Life Sciences Sciences and Technology: other

Job Description


Job #: G890

Posted Date: January 8, 2020

Closes On: Open Until Filled

Job Title: Research Assistant III – Electron Microscopy Specialty, Laboratory of Genetics, Dr. Lyumkis

Status: Regular Full Time

Benefits Eligible: Yes

Position Description:

The Research Assistant III position will focus on managing the lab’s activities in the cryo-electron microscopy (cryo-EM) facility, utilizing high-end equipment for cryo-EM, focused-ion-beam (FIB) milling, and light microscopy, performing computational image processing tasks, assisting users with data collection and analysis, training members of the laboratory, and managing the facility for the laboratory. A central component will be the day-to-day operation and management of the cryo-EM infrastructure, which includes multiple electron microscopes, a FIB milling instrument, a cryo-fluorescence microscope, as well as a number of ancillary equipment associated with cryo-EM. The employee will be the intermediary to the electron microscopy facility for the laboratory and will interact closely with members of the lab as well as the general facility manager for the electron microscopy suite. A second component will be utilizing the equipment, together with computational data analysis infrastructure in the lab, to examine and study the structures macromolecular assemblies. The research work will be performed with some supervision from postdoctoral associates, and there will also be an independent research component. A successful candidate will work part of their time with assisting users, training, etc., as well as dedicate part of their time on independent projects and part of their time on supporting postdoctoral researchers in the lab. The Research Assistant will be expected to apply expertise in the EM field and execute experiments and analyze experimental results independently with limited training in specific techniques and methods. The overall goal of the research is to decipher and understand macromolecular structures isolated from and inside of the native cellular environment.



  • Bachelor's degree in biological sciences, engineering, or related field or equivalent relevant work experience.



  • Minimum 4 years of relevant experience or equivalent combination of education and experience in laboratory techniques.
  • Proficient in the operation of standard lab equipment and computer hardware/software
  • Theoretical knowledge of microscopy
  • Track record of working part of a collaborative team
  • Practical hand-on knowledge of electron microscopy, computational image analysis

Special Requirements:

  • Must be able to work a flexible schedule and extended hours as needed to support research needs.
  • Must be willing to work in an animal-related research environment.
  • Satisfactory completion of the Institute’s background investigation.
  • Must be willing to sign a confidentiality agreement.

Physical Requirements:

This position requires constant adjusting focus, seeing, sitting and working inside.


Application Details

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Application Deadline

Open Until Filled