Bioinformatics Analyst II – Genomics Analysis Laboratory, Dr. Joseph Ecker

  • Salk Institute for Biological Studies
  • La Jolla, San Diego, CA, USA
  • Jan 08, 2020
Full time   Biology/Biotechnology/Life Sciences

Job Description


Job #: G851
Posted Date: January 8, 2020
Closes On: Open Until Filled
Job Title: Bioinformatics Analyst II – Genomics Analysis Laboratory, Dr. Joseph Ecker
Status: Regular Full Time
Benefits Eligible: Yes
Laboratory/Department: Genomic Analysis Laboratory
Position Description:

Large-scale-single-cell methylome profiling is the current state-of-art for studies that require the DNA methylation profiles at base resolution in heterogenous tissues. Single cell DNA methylation profiling offers the advantage of obtaining uniform genome wide coverage at cellular resolution. snmC-seq2 is an improved version of snmC-seq that provides better throughput, library complexity, coverage uniformity, and read mapping. This method is being used routinely in various projects including the DARPA-funded ECHO and MBA projects and several NIH projects for identifying DNA methylation patterns and their effects in samples such as blood cells and the brain.

The Bioinformatics Analyst II will work closely with other members of the project and the Ecker laboratory to advance the computational approaches involved in data analysis of snmC-seq datasets. The analyst will contribute directly to research projects by implementing, optimizing and executing the currently available pipelines that include mapping, QC, visualization, and reporting. Finally, the analyst will play part in administrating shared computer resources, such as compute and storage servers.


Education:

Required:

  • MS degree in bioinformatics, computational biology, computer science, biological sciences, bioengineering, mathematics, statistics or related discipline or equivalent relevant experience.

Preferred:

  • PhD degree in bioinformatics, computational biology, computer science, biological sciences, bioengineering, mathematics, statistics or related discipline or equivalent relevant . experience.

Experience:

Required:

  • Typically requires a minimum of 3 years of relevant bioinformatics or programming experience with a Master’s degree. If PhD, experience acquired through PhD program may be considered in lieu of professional experience.
  • Relevant experience acquired through education and/or profession must include: proficiency in Python programming; fluency in at least 2 common programming languages (Bash, AWK, or R); next-generation sequencing technologies and assays; and high performance computing (e.g., SGE environment)
  • Experience with making presentations to and communicating effectively with various levels of staff.

Preferred:

  • Minimum of 1 year analysis experience on DNA methylation datasets and/or single cell datasets
  • Minimum of 2 years analysis experience with NGS / High-throughput sequencing data analysis
  • Experience in statistics and machine learning.
  • Experience in biology.

Special Requirements:
  • Satisfactory completion of the Institute’s background investigation.
  • Must be willing to sign confidentiality agreement.
  • Must be willing to work in an animal-related research environment.

Physical Requirements:

This role requires constant adjusting focus, grasping, handling, hearing, keying, seeing, sitting, talking, touching, feeling, analyzing, calculating, communicating, reading, reasoning, writing and working inside.


Application Details

When inquiring or applying for this position, please also reference AcademicCareers.com

Applicants with dual-career considerations can find university jobs such as professor jobs, dean jobs, chair / department head jobs, and other faculty jobs and employment opportunities within the Dallas County Community College District and at other institutions of higher education in the region on www.AcademicCareers.com

Application Deadline

Open Until Filled