The Engle Lab focuses on understanding the etiology of pancreatitis and pancreatic cancer to develop better prevention, diagnostic, and treatment strategies. We study the impact of altered glycosylation on the cross-talk between ductal cells with their microenvironment during disease pathogenesis as well as the role of tobacco-related carcinogens in priming the pancreas for transformation. We rely heavily on three-dimensional organoid mono- and co-culture systems as well as genetically engineered mouse models.
Fully funded Post-doctoral positions are immediately available for individuals with a good understanding of cancer and disease modeling. Ideal candidates should be intellectually curious, well-organized and well-versed in constructive problem solving. Experience with cell culture and mouse modeling is preferred.
Ph.D. or M.D./Ph.D. in Biological Sciences or related fields.
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