Employment History Include your last ten (10) years of employment history, or length of your employment history if less, including all position (even those that are not relevant to this position) and periods of unemployment. Incomplete information could disqualify you from further consideration.
Large-scale-single-cell methylome profiling is the current state-of-art for studies that require the DNA methylation profiles at base resolution in heterogenous tissues. Single cell DNA methylation profiling offers the advantage of obtaining uniform genome wide coverage at cellular resolution. snmC-seq3 is an improved version of snmC-seq that provides better throughput, library complexity, coverage uniformity, and read mapping. This method is being used routinely in various projects including the DARPA-funded ECHO and MBA projects and several NIH BRAIN projects for identifying DNA methylation patterns and their effects in samples such as blood cells and the brain.
The Bioinformatics Analyst II will work closely with other members of the project and the Ecker laboratory to advance the computational approaches involved in data analysis of snmC-seq datasets. The analyst will contribute directly to research projects by implementing, optimizing and executing the currently available pipelines that include mapping, QC, visualization, and reporting. The analyst will be required to develop advanced computational and statistical methods for big-data analysis. The analyst will be expected to create and implement machine learning algorithms for identifying patterns and signatures relevant to biological datasets. Finally, the analyst will play part in administrating shared computer resources, such as compute and storage servers.
Bioinformatics Analysis (85%)
Research Design and Presentation (5%)
Maintenance and Management of Bioinformatics Resources (10%)
SKILLS AND ABILITIES
SPECIAL CONDITIONS OF EMPLOYMENT
This position requires constant adjusting focus, grasping, handling, hearing, keying, seeing, sitting, talking, touching/feeling, analyzing, calculating, communicating, reading, reasoning, writing and working inside.
Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities
The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information. 41 CFR 60-1.35(c)
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